A promising ex vivo liver protection strategy: machine perfusion and repair
نویسندگان
چکیده
منابع مشابه
Metabolic profiling during ex vivo machine perfusion of the human liver.
As donor organ shortages persist, functional machine perfusion is under investigation to improve preservation of the donor liver. The transplantation of donation after circulatory death (DCD) livers is limited by poor outcomes, but its application may be expanded by ex vivo repair and assessment of the organ before transplantation. Here we employed subnormothermic (21 °C) machine perfusion of d...
متن کاملTechnique of Subnormothermic Ex Vivo Liver Perfusion for the Storage, Assessment, and Repair of Marginal Liver Grafts
The success of liver transplantation has resulted in a dramatic organ shortage. In most transplant regions 20-30% of patients on the waiting list for liver transplantation die without receiving an organ transplant or are delisted for disease progression. One strategy to increase the donor pool is the utilization of marginal grafts, such as fatty livers, grafts from older donors, or donation aft...
متن کاملA new strategy and system for the ex vivo ovary perfusion and cryopreservation: An innovation
Children and young adults, who suffer from cancer, receive gonadotoxic therapy, which destroys their fertile abilities after survival. Ovarian cryopreservation and transplantation provide the promising solution to this problem, where the ovary can be removed before the gonadotoxic therapy and reimplanted after patient's survival, where the ovary is to be cryopreserved during the period of the t...
متن کاملTitle Ex Vivo Repair and Renal
Ex vivo repairs and renal autotransplantations were performed in three cases of renovascular disease. The first 2 cases consisted of stf'nosis of renal artery, one duぞ toTAKAYASU’s disease and the other due to atherosclerosis. The third (川ewas an aneurysm of renal artery. In al three caメesex vivo repaires of renal arterie:、司 coupledwith renal autotransplantations to ipsilateral iliac fossa were...
متن کاملEx vivo lung perfusion in Brazil
OBJECTIVE To evaluate the use of ex vivo lung perfusion (EVLP) clinically to prepare donor lungs for transplantation. METHODS A prospective study involving EVLP for the reconditioning of extended-criteria donor lungs, the criteria for which include aspects such as a PaO2/FiO2 ratio < 300 mmHg. Between February of 2013 and February of 2014, the lungs of five donors were submitted to EVLP for u...
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ژورنال
عنوان ژورنال: HepatoBiliary Surgery and Nutrition
سال: 2019
ISSN: 2304-3881,2304-389X
DOI: 10.21037/hbsn.2019.03.07